What You Need To Know About Inflammation

Comments (20)

Inflammation is not a disease.

Inflammation is best described as a defense mechanism to
limit tissue damage. It can be caused by infection, injury
or immune conditions. In each case, the inflammation is the
result of your immune system responding to another event.

When such an event occurs, a special cell called a
neutrophil targets the damaged cells and releases a
proinflammatory cytokine ( a natural substance used by the
body for immune regulation ). This attracts more neutophil
and begins a cycle of communication between neutrophil and
macrophage ( a type of cell in your immune system that works
to protect against infection and from toxins ). These
signals are generated using structures composed of
glyconutrients. This cycle would apply to the inflammation
of the cells in a vein, the thyroid, intestine, liver, a
muscle, the scalp, or any other collection of cells that are
given a name.

When we take a drug or an herbal to "stop inflammation," we
are really interrupting the natural process where the body
is sending out signals to other helper cells to say "Hey,
come deal with this." We are also interrupting the natural
process where the body is sending signals to us saying "take
it easy, we have something that needs care." Certainly
inflammation can be a discomfort and an annoyance but the
importance of inflammation as part of the immune response
cannot be overstated.

After the immune cells have cleared out the source of the
inflammation, additional immune cells begin a clean up
process and engulf dead neutrophils and other cellular
debris. If the process is successful, the body will return
to normal levels of cells and mediators.

Inflammation is affected by diet in that certain nutrients
play a role in the normal inflammation process. Various
glyconutrients are used to construction glycoforms for
signaling in the body and antioxidants bind to free radicals
which may either be the source, or by product of, the

In summary, inflammation is a normal cellular process. Your
body induced inflammation in response to something else.
While the process can lead to discomfort, it should be
understood that medications and herbs which mask the
inflammation by interfering with it may also be interfering
with the underlying immune response. Work with your doctor
to manage your symptoms in the short term but then also
factor in diet and lifestyle changes to help support the
natural processes of the body. Every cell in your body has
the natural ability to restore, protect and defend itself.
Don't just turn them off for good. Studies have shown that
concentrations of glyconutrients can have a very beneficial
effect on inflammation. While the processes are still being
studied, non-toxic glyconutrient supplements have been
available to the public for over 10 years.

About the Author

Dave Saunders is a certified nutritional educator, wellness
coach and author. He is also the host of a weekly, nation-wide
telephone lecture on health and nutrition. For additional
information, please visit www.glycoboy.com or email Dave at


This is not madness 31.12.2010. 19:20

How do necrotic cells lead to inflammation? I know that apoptosis never lead to inflammation, instead necrosis can lead to inflammation.
However I can't understand in which way necrosis cause inflammation: maybe necrotic cells are phagocytated by macrophages and these start the inflammation?

Besides is a necrotic event always needed to have an inflammation?

Ok, but in which way the molecules that are released by necrotic cells induce inflammation?
How do these molecules manage to attract granulocytes?

This is not madness

Admin 31.12.2010. 19:20

As cells die from necrosis, they release their cytoplasmic constituents into the surrounding tissue. These molecules begin the process of inflammation, attracting neutrophils to the site of cell death, and activating the complement cascade. As neutrophils enter the area, they release proteolytic enzymes and other active molecules, further increasing the inflammatory response. Apoptotic cells are neatly phagocytized, and so don't induce inflammation.


Carlos F 04.04.2009. 22:49

What is a simple remedy to decrease or get rid of inflammation? My mom has a specific inflammation that she's gotten from working in a factory. She has to tear down tape from boxes, and it really works her hands out. She doesn't work on Saturdays or Sundays though.
What is a good remedy that won't require things normally not found at home that could get rid of, or at least lessen the inflammation?
Cold water? Warm water?

Carlos F

Admin 04.04.2009. 22:49

Aspirin is still the drug of choice for inflammation. I would suggest that your mother take a single aspirin in the morning before work to reduce the inflammation. Keeping her hands warm will help to reduce the pain.


suri80 03.07.2009. 00:15

What are the symptoms of small intestine inflammation? What are the symptoms of small intestine inflammation?
And can it be chronic?
And where is the pain usually located?
And can CT scan reveal such inflammation?


Admin 03.07.2009. 00:15

Usually pain typically after eating in your lower abdomen. CT scan can reveal the inflammation. If its Crohn's Disease it is Chronic and you should have a GI do an endoscopy and colonoscopy for more answers


Shaik 09.03.2008. 15:54

What'll be the effect of discontinuing Isotretinoin capsules due to skin inflammation and rashes? Dermetologist has suggested these for treatment of acne. I'm getting skin rashes and inflammation due to the usage of these. Can any one suggest whether there'll be any side effects if we stop the usage of these?


Admin 09.03.2008. 15:54

The rashes and inflammation will go away, but your acne will probably come back.


Isabella Almanza 17.05.2011. 17:27

Does the the inflammation of the liver causes pain in your stomach? I went to the doctor and he did me an ultra sound. When he got the results he told me I had liver inflammation. For several years I've been having some strange and painful stomachaches is this the cause of my inflammation of liver? I would like to know so I can know what to do for it.

Isabella Almanza

Admin 17.05.2011. 17:27

No, liver inflammation causes no pain. The liver itself has no nerve endings, therefore, no pain. That's why people can have cirrhosis of the liver and not even know it. I had no idea anything was wrong with me until my liver was already 90% destroyed due to many many years of constant inflammation caused by an autoimmune disease. The only way I knew something was wrong was because I suddenly swelled up with a lot of fluid. I had liver failure and a liver transplant and never experienced any liver pain. Now there is a sac around the liver that can cause some pain, but it never gave me any problems. People are just not aware when their liver is inflamed because they have no symptoms. By the time any physical symptoms of liver failure appears, the failure is often far advanced.

What can you do about it? Find out the real reason your stomach hurts. What can you do about liver inflammation? It depends on what is causing it to inflame in the first place. If you can get rid of whatever is irritating it, then the inflammation will go away. Example: If alcohol abuse is causing it, then stop drinking and it should go away as long as no permenent liver damage has been done yet such as cirrhosis. Example: My liver inflammation was caused by an autoimmune disease in which there is nothing I can do to stop it. It depends on the cause and whether or not you can get rid of the irritant.

You need to discuss this with your doctor and find out what your options are for treating both problems such as your stomach and inflamed liver. I'm no doctor, but in my opinion they are going to be two separate problems in which both need addressed. You should not have to go for years with stomach pain and not know what is causing it. Hopefully, you can get the help you need by following up with your doctor and demanding some answers. If this doctor cannot help you, then find one who will.


Michael 16.10.2009. 19:50

What is the relationship between exercise and inflammation in the body? What is the relationship between exercise and inflammation (the inflammatory response to antigens or tissue damage; and inflammatory states or processes in general) in the body?


Admin 16.10.2009. 19:50

Many scientists have expressed concern that hard exercise damages muscles, so it may turn on inflammation and harm you. However, a study from Verona, Italy shows that hard exercise does not cause inflammation. Inflammation is a healthy process that comes to the body?s aid when it?s injured.
Delayed onset muscle soreness is thought to be a result of microscopic tearing of the muscle fibers. Muscles soreness stems from small tears in the muscle fibers that are aggravated by post-exercise muscle cell inflammation.

When tissue cells become injured they release a number of chemicals that initiate the inflammatory response. Examples of these are kinins, prostroglandins and histamine. These chemicals work collectively to cause increased vasodilation (widening of blood capillaries) and permeability of the capillaries. This leads to increased blood flow to the injured site. These substances also act as chemical messengers that attract some of the body's natural defense cells- a mechanism known as chemotaxis.

Although highly beneficial to the body's defense strategies some chemicals also increase the sensitivity of the pain fibres in the area and so the area becomes painful.

Chemotaxis leads to the migration of certain white blood cells (leukocytes) to the damaged area. Two types of leukocyte are predominantly in the inflammatory response- macrophages and neutrophils. Neutrophils are first to the injured site and function by neutralizing harmful bacteria. Macrophages aid the healing process by engulfing bacteria and dead cells and ingesting them so that the area is clear for new cells to grow. They arrive at the injured site within 72 hours of the injury and may remain in the area for weeks after the injury.


Karly 18.11.2012. 22:13

What is rheumatoid arthritis an inflammation of? I need help finishing this question for an anatomy class - can anyone help me? :)

In rheumatoid arthritis, the initial pathology is inflammation of the _____.

The question is true or false, and the answer already filled in is bursae; is that right? And, if not, what should I change it to? Thank you!


Admin 18.11.2012. 22:13

arthritis means inflammation of joints. Inflammation of the Bursae would be bursitis.


Kavi 06.10.2009. 06:11

What is the difference between inflammation and swelling? Does Inflammation means just pain and ache in the? joints? I have sharp pain in all of my body joints but no swelling. Is that called inflammation? inflammation = just pain and ache but no swellling?


Admin 06.10.2009. 06:11

You can have inflammation but not see the swelling, it can be inside. Inflammation and swelling are the same thing.


sana1995@sbcglobal.net 05.02.2006. 20:55

What is the meaning of inflammation and immuse system? sentance: Health experts believe that inherited, environmental, and immune system factors combine to cause inflammation of the bronchial tubes, which carry air to the lungs.


Admin 05.02.2006. 20:55

immune systen is the defense system of the body and inflammation is a way of responding to various harmful stimuli. it is mediated at the cellular level and it involves a lot of complex processes and chemicals like histamine and the like. i think its bronchoconstriction that ur talking about, ya it could be inherited, environmental and immunological. Asthma is a good example.


Tralala Unicorns 19.06.2013. 13:02

What does inflammation in the ear actually mean? I went to the doctors and they told me that I have inflammation in my ear. Because I live in japan the only doctors around here are Japanese and didn't really eplain it well to me (though they did try their best). So, now the doctor is suggesting she does regular ear cleaning..3 times a week. The eperience is like going to the dentist where she uses an instrument to "suck up" whatever, and then either sprays warm water or waz inside my ear, before dipping a cotton bud in medicine and applying it deeep inside (kinda hurts).

Anyway, that is the cleaning process that she recommends I have for 3 times a week. She thinks this will help remove bacteria? And what is this cleaning process called?

BUT what does Inflammation in the ear actually mean?

Oh and some of my symptoms were:
Ear discharge- usually yellow
Some pain - but not all the time, and not enough to make me cry

That's all i've noticed so far. Any ideas?

Thank you!

Tralala Unicorns

Admin 19.06.2013. 13:02


Otitis externa is an inflammation of the ear canal. The inflammation may be caused by infection, allergy or other causes. Treatment with ear drops is usually effective.

What is otitis externa?

Otitis means inflammation of the ear. The inflammation is usually due to an infection. Otitis externa means that the inflammation is confined to the ear canal and does not go further than the eardrum.

What causes otitis externa?

otitis externa is an infection of the skin of the ear canal and is very common. It often occurs 'out of the blue' for no apparent reason.

In general, the infections are caused by a bacterial infection. Occasionally, they can be due to a fungal or yeast infection.

Some people are more prone to otitis externa. If you get water, shampoo, soap, hairspray, etc, in an ear then it may cause it to itch. You may then scratch or poke the ear. This can damage the skin in the ear canal and cause inflammation. Inflamed skin can quickly become infected. A vicious circle may then develop. The inflammation and infection cause more itch, you then scratch more, which then can makes things worse.

What are the symptoms of otitis externa?

The symptoms of otitis externa can vary between cases. Common symptoms include itch, ear discharge, temporary dulled hearing and pain. Your ear may feel blocked or full. One or both ears can be affected.
Sometimes the glands in your neck or around your ear can become enlarged and sore.
Although it is more common for only one ear to be affected, in some cases both ears become infected.

What is the treatment for otitis externa?

Most people with otitis externa are given treatment without having any tests as the diagnosis is usually clear from examination of your ear.
However, your doctor or nurse may decide to take a swab (specimen of the discharge) to find out which germ is causing the infection. This helps to guide the choice of antibiotic ear drops to use.


Write a comment

* = required field





* Yes No